There are 25 6-letter words that start with 'spe'.
| speaks | speans | spears | specie | specks |
| speech | speedo | speeds | speedy | speels |
| speers | speils | speirs | speise | speiss |
| spells | spelts | speltz | spence | spends |
| spendy | spense | sperms | spewed | spewer |
Note: These 25 6-letter words that start with 'spe' are found from the USA & Canada version of the tournament Scrabble word list.
Also see words start with spec, spee, sper, spea, spel, spen, spei, spew, spes, sped.
4-letter words start with 'spe' (3)