There are 336 12-letter words that start with 'de'.
Note: These 336 12-letter words that start with 'de' are found from the USA & Canada version of the tournament Scrabble word list.
Also see words start with dec, des, def, dem, dep, del, det, den, dea, dev, der, deb, deg, dee, dei, dew, deh, deo, deu, ded, dex, dek, dej, dez, dey.
3-letter words start with 'de' (9)