There are 17 words that start with 'spru'.
| sprue | sprug | spruce |
| sprucy | sprues | sprugs |
| sprung | spruced | sprucer |
| spruces | sprucely | sprucest |
| sprucier | sprucing | spruciest |
| spruceness | sprucenesses | |
Note: These 17 words that start with 'spru' are found from the USA & Canada version of the tournament Scrabble word list.