There are 15 words that start with 'destru'.
| destruct | destructs | 
| destructed | destructing | 
| destruction | destructive | 
| destructible | destructions | 
| destructively | destructivity | 
| destructionist | destructibility | 
| destructionists | destructiveness | 
| destructivities | |
Note: These 15 words that start with 'destru' are found from the USA & Canada version of the tournament Scrabble word list.