There are 21 words that end with 'yme'.
| cyme | zyme | chyme |
| rhyme | thyme | enzyme |
| berhyme | isozyme | coenzyme |
| lysozyme | ribozyme | synonyme |
| apoenzyme | exoenzyme | monorhyme |
| isoenzyme | proenzyme | holoenzyme |
| mesenchyme | endoenzyme | multienzyme |
Note: These 21 words that end with 'yme' are found from the USA & Canada version of the tournament Scrabble word list.